Nucleophilic 5-endo-trig cyclizations of N-homoallylic sulfonamides: a facile method for the construction of pyrrolidine rings.
نویسندگان
چکیده
Normally disfavored 5-endo-trig cyclizations proceed in N-homoallylsulfonamides bearing a CF(3), CCl(3), CO(2)Et or CN group at the C-3 position, via an intramolecular S(N)2'-type or addition reaction to construct pyrrolidine rings, even though the system allows a more favorable 5-exo-trig pathway.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 26 شماره
صفحات -
تاریخ انتشار 2007